What ever your in the mood for in Las Vegas there is a nightclub for you.
Some of the best nightclubs I have heard about are: LAX, Pure, The Bank, Rain, Jet, Studio 54, Tao, Coyote Ugly and many many more!!
Here are a couple videos I found on some of these nightclubs for you all to check out.
Coyote Ugly
Studio 54
Pure
All of these clubs look like a good time to me. Maybe one of these days I will find out personally if they really are or not. A few people I know have gone to Vegas and they all went clubbing of course. I guess it is needless to say but they had a great time!